Aquaporins in Health and Disease: New Molecular Targets for - download pdf or read online

By Graca Soveral,Soren Nielsen,Angela Casini

Since the invention of Aquaporin-1 (AQP1) as a water channel, many experiences have published the significance of aquaporins in mammalian body structure and pathophysiology in addition to plant and microbial biology. The reviews have additionally proven aquaporins as capability drug pursuits and goals for bettering crop properties.

Written via a global workforce of members on the leading edge of the sector, Aquaporins in well-being and illness: New Molecular ambitions for Drug Discovery offers the newest study advances in aquaporins and different significant intrinsic protein (MIP) channels. the 1st part of the e-book describes the final options of aquaporin channel functionality, genomic examine, structure-function research of aquaporins and glycerol facilitators, and law through gating and trafficking, together with yeast aquaporin legislation and serve as. the second one part discusses the physiological and pathophysiological roles of aquaporins in people and microbes. the ultimate part covers the improvement of inhibitors of aquaporin functionality. The book’s epilogue deals destiny views and instructions, customarily within the zone of aquaporin-based diagnostics and therapeutics.

Stimulating destiny study in this very important protein relations, this booklet enables a paradigm shift within the figuring out and roles of aquaporin membrane proteins in all organic settings. It encourages scientists to advance novel ways for the therapy of human ailments according to aquaporin functionality or dysfunction.

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Aquaporins in Health and Disease: New Molecular Targets for Drug Discovery by Graca Soveral,Soren Nielsen,Angela Casini

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